Biological imaging (infrared nuclear magnetic CT)
Functional modification of quantum dots
There are three main types:
1. Surface ligand exchange, using ligands with water-soluble groups to replace ligands on the surface of hydrophobic quantum dots.
2. Polymer encapsulation, the hydrophobic part of the polymer molecule and the long-chain alkanes on the surface of the quantum dots form micelles through van der Waals interaction to encapsulate the quantum dots.
3. The silica layer is wrapped, and the hydrophobic ligands on the surface of the quantum dots are generally replaced with silane containing mercapto groups.
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Beike Nano provides molecular coupling services for surface modification of quantum dots
1. The surface of quantum dots is modified by small drug molecules
According to customer needs, load oil-soluble or water-soluble drug molecules on the surface of quantum dots, such as doxorubicin, paclitaxel, cisplatin, camptothecin, salbutamol, enrofloxacin, gentamicin, etc.
2. Surface modification of quantum dots with functional small molecules
On the basis of existing products on sale, small biological targeting molecules, such as RGD and folic acid, can be coupled to the surface of quantum dots to construct targeted nanoprobes according to customer needs.
3. Quantum dot surface modification antibody
On the basis of existing products on sale, protein molecules such as bio-targeted antibodies, such as rituximab (for CD20), cetuximab (for EGFR), and trastuzumab (for HER2), etc., coupled to the surface of quantum dots to construct targeted nanoprobes.
4. Surface modification of quantum dots with small sugar molecules
On the basis of existing products on sale, small sugar molecules such as galactose, glucose, rhamnose, fructose, maltose, mannose, xylose, raffinose, stachyose, arabinose can be added according to customer needs , Fucose, glucuronic acid, etc., are coupled to the surface of quantum dots to construct targeted nanoprobes.
There are three main types:
1. Surface ligand exchange, using ligands with water-soluble groups to replace ligands on the surface of hydrophobic quantum dots.
2. Polymer encapsulation, the hydrophobic part of the polymer molecule and the long-chain alkanes on the surface of the quantum dots form micelles through van der Waals interaction to encapsulate the quantum dots.
3. The silica layer is wrapped, and the hydrophobic ligands on the surface of the quantum dots are generally replaced with silane containing mercapto groups.
picture
Beike Nano provides molecular coupling services for surface modification of quantum dots
1. The surface of quantum dots is modified by small drug molecules
According to customer needs, load oil-soluble or water-soluble drug molecules on the surface of quantum dots, such as doxorubicin, paclitaxel, cisplatin, camptothecin, salbutamol, enrofloxacin, gentamicin, etc.
2. Surface modification of quantum dots with functional small molecules
On the basis of existing products on sale, small biological targeting molecules, such as RGD and folic acid, can be coupled to the surface of quantum dots to construct targeted nanoprobes according to customer needs.
3. Quantum dot surface modification antibody
On the basis of existing products on sale, protein molecules such as bio-targeted antibodies, such as rituximab (for CD20), cetuximab (for EGFR), and trastuzumab (for HER2), etc., coupled to the surface of quantum dots to construct targeted nanoprobes.
4. Surface modification of quantum dots with small sugar molecules
On the basis of existing products on sale, small sugar molecules such as galactose, glucose, rhamnose, fructose, maltose, mannose, xylose, raffinose, stachyose, arabinose can be added according to customer needs , Fucose, glucuronic acid, etc., are coupled to the surface of quantum dots to construct targeted nanoprobes.
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