CPDDs

CPDDs

【Numbering】BKME110002 【CAS】CAS
【Item No.】BKME110002-2 【specification】
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Name: CPDDs
Composition: digoxin (DIG) + doxorubicin (DOX) + PLGA nanoparticles
Grain size: 50-200nm
Application: anti-tumor and tumor metastasis
Storage conditions: -4℃

Other instructions: Half shelf life under sealed state [Main advantages] CPDD can accurately target homologous primary tumor cells and CTC clusters in blood and lymphatic circulation, and induce intracellular Ca 2 + accumulation by inhibiting Na + / K + -ATP enzyme, which helps to inhibit cell-cell junctions to break down CTC clusters. CPTT inhibits the epithelial-stromal transition process, thereby inhibiting escaping tumor cells from the primary site.

Title:Cancer-specific calcium nanoregulator suppressing the generation and circulation of circulating tumor cell clusters for enhanced anti-metastasis combinational chemotherapy
Article link:https://doi.org/10.1016/j.apsb.2021.04.009


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