HA-M@AT@GP
| 【Numbering】BKMC101007 | 【CAS】CAS | ||
| 【Item No.】BKMC101007-2 | 【specification】 | ||
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Name: HA-M@AT@GP
Composition: GOQDs, AT, and LPS
Grain size: 50-100nm
Application: Targeting and promoting atherosclerosis regression by reducing inflammation and enhancing autophagy
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [main advantages] 1. Hybrid membrane coating strategy not only retains the immune escape and active accumulation of nanomaterials to inflammatory plaques, but also increases the penetration of plaques; 2. HA modification can further improve the efficiency of nanosheets by activated macrophages in atherosclerotic plaques. The acidic environment of atherosclerotic plaque promotes the release of drugs and maintains high drug concentration in the plaque to maintain high drug concentration in the lesion site; 3, the combination of targeted inflammatory plaque and the uptake of highly activated macrophages showed high antiatherosclerosis during low-dose treatment, with no significant myocardial or hepatotoxic effects.
Title:Targeting and promoting atherosclerosis regression using hybrid membrane coated nanomaterials via alleviated inflammation and enhanced autophagy
Article link:https://mp.weixin.qq.com/s?src=11×tamp=1688544166&ver=4631&signature=m3*tmamJRv5kEXld51LYdkuIj8ioJGpElI8Iu090k1b6yvpHYiYQoBflV8vPkgN29B1viBGEUPGSFckpzMKYjUW*pFKORE5hhTpShAvI4xV6aaVER-kGFHAlBkxpTR2S&new=1
Message
Composition: GOQDs, AT, and LPS
Grain size: 50-100nm
Application: Targeting and promoting atherosclerosis regression by reducing inflammation and enhancing autophagy
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [main advantages] 1. Hybrid membrane coating strategy not only retains the immune escape and active accumulation of nanomaterials to inflammatory plaques, but also increases the penetration of plaques; 2. HA modification can further improve the efficiency of nanosheets by activated macrophages in atherosclerotic plaques. The acidic environment of atherosclerotic plaque promotes the release of drugs and maintains high drug concentration in the plaque to maintain high drug concentration in the lesion site; 3, the combination of targeted inflammatory plaque and the uptake of highly activated macrophages showed high antiatherosclerosis during low-dose treatment, with no significant myocardial or hepatotoxic effects.
Title:Targeting and promoting atherosclerosis regression using hybrid membrane coated nanomaterials via alleviated inflammation and enhanced autophagy
Article link:https://mp.weixin.qq.com/s?src=11×tamp=1688544166&ver=4631&signature=m3*tmamJRv5kEXld51LYdkuIj8ioJGpElI8Iu090k1b6yvpHYiYQoBflV8vPkgN29B1viBGEUPGSFckpzMKYjUW*pFKORE5hhTpShAvI4xV6aaVER-kGFHAlBkxpTR2S&new=1
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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