NP2
| 【Numbering】BKME108009 | 【CAS】CAS | ||
| 【Item No.】BKME108009-2 | 【specification】 | ||
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Name: NP2
Composition: pH response and glutathione [GSH] response to nanoparticles, zoledronic acid
Size: 100-200nm
Application: Anti-osteosarcoma
Storage conditions: -4℃
Other instructions: Half-year shelf life under sealed state [Main advantages] NP2 remodels the inhibitory TME assisted by ZA, reduces myeloid-derived inhibitory cells (MDSCs) and regulatory T cells (Tregs), and repolarize tumor-associated macrophages (TAMs). Meanwhile, NP2 can increase the expression of programmed death ligand 1 (PD-L1) on the surface of tumor cells, showing the good inhibitory effect of immune checkpoint blockade (ICB) immunotherapy on tumor growth.
Message
Composition: pH response and glutathione [GSH] response to nanoparticles, zoledronic acid
Size: 100-200nm
Application: Anti-osteosarcoma
Storage conditions: -4℃
Other instructions: Half-year shelf life under sealed state [Main advantages] NP2 remodels the inhibitory TME assisted by ZA, reduces myeloid-derived inhibitory cells (MDSCs) and regulatory T cells (Tregs), and repolarize tumor-associated macrophages (TAMs). Meanwhile, NP2 can increase the expression of programmed death ligand 1 (PD-L1) on the surface of tumor cells, showing the good inhibitory effect of immune checkpoint blockade (ICB) immunotherapy on tumor growth.
Title:Dual-responsive nanoparticles targeting bone microenvironment for synergistic chemoimmunotherapy of osteosarcoma by remodeling immune microenvironment
Article link:https://doi.org/10.1016/j.nantod.2023.101877| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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