CISAR
| 【Numbering】BKMC106015 | 【CAS】CAS | ||
| 【Item No.】BKMC106015-2 | 【specification】 | ||
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name:CISAR
Composition: copper and ferric silicate (CIS) + gold nanoparticles + immunoagonist R848
Grain size: 50-100nm
Application: Tumor therapy
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] The introduction of copper ions and hypertherapy caused by laser irradiation improve the efficiency of ROS generation, thus greatly enhancing ferroptosis. CISAR showed superior Fenton catalytic activity at pH 6.5, with a maximum velocity (Vmax) of 19.3107Ms 1 at 55 C and about 30 times that of iron silicate nanoparticles (IS NPs) at 25 C. Subsequently, the maturation of DCs is stimulated and a further immune response is generated by loading with the immune agonist R848 (CISAR).
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Composition: copper and ferric silicate (CIS) + gold nanoparticles + immunoagonist R848
Grain size: 50-100nm
Application: Tumor therapy
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] The introduction of copper ions and hypertherapy caused by laser irradiation improve the efficiency of ROS generation, thus greatly enhancing ferroptosis. CISAR showed superior Fenton catalytic activity at pH 6.5, with a maximum velocity (Vmax) of 19.3107Ms 1 at 55 C and about 30 times that of iron silicate nanoparticles (IS NPs) at 25 C. Subsequently, the maturation of DCs is stimulated and a further immune response is generated by loading with the immune agonist R848 (CISAR).
Title:A “Closed-Loop” Therapeutic Strategy Based on Mutually Reinforced Ferroptosis and Immunotherapy
Article link:https://doi.org/10.1002/adfm.202111784
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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