ZnP@DHA/PyroFe
| 【Numbering】BKMC106008 | 【CAS】CAS | ||
| 【Item No.】BKMC106008-2 | 【specification】 | ||
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Name: ZnP @ DHA / PyroFe
Composition: Cholesterol derivative of DHA (choll-DHA) + iron pyrophosphate (Pyro-Fe) + ZnP
Grain size: 50-150nm
Application: anti-tumor
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [Main advantages] ZnP @ DHA / coke iron particles stabilize DHA against hydrolysis, prolong the blood circulation of cholesterol-DHA and coke iron, and promote their absorption by tumors. Co-delivery of exogenous iron complexes and DHA induces more ROS production and causes significant tumor suppression in vivo. By enhancing tumor immunogenicity, the combination of DHA and pyroiron may sensitize non-immunogenic colorectal tumors to antipd-l1 checkpoint blocking immunotherapy.
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Composition: Cholesterol derivative of DHA (choll-DHA) + iron pyrophosphate (Pyro-Fe) + ZnP
Grain size: 50-150nm
Application: anti-tumor
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [Main advantages] ZnP @ DHA / coke iron particles stabilize DHA against hydrolysis, prolong the blood circulation of cholesterol-DHA and coke iron, and promote their absorption by tumors. Co-delivery of exogenous iron complexes and DHA induces more ROS production and causes significant tumor suppression in vivo. By enhancing tumor immunogenicity, the combination of DHA and pyroiron may sensitize non-immunogenic colorectal tumors to antipd-l1 checkpoint blocking immunotherapy.
Title:Co-delivery of dihydroartemisinin and pyropheophorbide-iron elicits ferroptosis to potentiate cancer immunotherapy
Article link:https://doi.org/10.1016/j.biomaterials.2021.121315
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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