BSO/ZIF-8@Au@MPN@HA

BSO/ZIF-8@Au@MPN@HA

【Numbering】BKMC106000 【CAS】CAS
【Item No.】BKMC106000-2 【specification】
5 minutes to choose the product plan

E-mail:beikenano@gmail.com




Name: BSO / ZIF-8 @ Au @ MPN @ HA
Composition: l-buthionine-sulfoxide (BSO) + Fe ion + ZIF-8 + HA + gold nanoparticles
Size: 100-300nm
Application: Enhance the effect of radiotherapy
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] Tumor microenvironment (TME) can degrade nanohybrids, combined with iron apoptosis induction and high-z effect based on metal-organic frame, for iron apoptosis enhanced RT in TNBC. The l-butanionine-sulfoxide (BSO) can inhibit the biosynthesis of glutathione (GSH), inactivate glutathione peroxidase 4 (GPX 4), thus destroying the apoptosis defense system. The delivered ferrous ion can become a potent apoptosis executor by triggering Fenton reaction; the combination can induce potent ferroptosis and cooperate with the radiosensitization mediated by surface-modified gold (Au) nps to improve the efficacy of radiotherapy.


Title:A MOF-based Potent Ferroptosis Inducer for Enhanced Radiotherapy of Triple Negative Breast Cancer

Article link:https://doi.org/10.1021/acsnano.3c00048




Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance

Message

Name: *
Mobile: *
E-mail: *
Content:
 
Scan code concerns WeChat official account
QQCommunication group:1092348845
Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately.
    No video

Previous: the end...

Next: 仿生巨噬细胞膜载CRISPR/Cas9

advisory
phone
Tel:+86-18915694570
scan

scan
WeChat