Bioprobe：PPa-RGD
| 【Numbering】BKMD107001 | 【CAS】CAS | ||
| 【Item No.】BKMD107001-2 | 【specification】 | ||
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Name: PPa-RGD
Composition: PPa RGD
Grain size: 50-100nm
Application: Glioma in situ
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] With the help of a large number of cRGD targeting groups present on the surface, Crossing the blood-brain barrier (BBB), And targeted delivery to in situ glioma cells (U87MG and U251), On the one hand, enhanced MRI contrast signals are used to locate in situ gliomas in the brain; on the other hand, In the presence of high intracellular concentrations of glutathione in brain glioma cells, Rapid disassembly occurs, And the release of a near-infrared photosensitizer (PPa), Thus restoring the photodynamic therapeutic function, And generate enhanced NIR fluorescence signal to monitor drug release and accumulation.
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Composition: PPa RGD
Grain size: 50-100nm
Application: Glioma in situ
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] With the help of a large number of cRGD targeting groups present on the surface, Crossing the blood-brain barrier (BBB), And targeted delivery to in situ glioma cells (U87MG and U251), On the one hand, enhanced MRI contrast signals are used to locate in situ gliomas in the brain; on the other hand, In the presence of high intracellular concentrations of glutathione in brain glioma cells, Rapid disassembly occurs, And the release of a near-infrared photosensitizer (PPa), Thus restoring the photodynamic therapeutic function, And generate enhanced NIR fluorescence signal to monitor drug release and accumulation.
Title:Controlling Disassembly of Paramagnetic Prodrug and Photosensitizer Nanoassemblies for On-Demand Orthotopic Glioma Theranostics
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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