Name: CRANAD-61
Raw material: oxalate curcumin derivative excitation/emission wavelength: 675/760nm Application: ROS detection
Storage condition: -4℃
Other notes: Shelf life of half A year under seal [Main advantage] The molecular probe can not only detect ROS concentration in the brain at a macro level, but also detect ROS concentration around Aβ plaques at a microscopic level through two-photon imaging. CRANAD-61 reacts with ROS in AD's brain to cause A blue shift in the spectrum, which is a "visible" to "invisible" shift in overall animal imaging and can be used to identify "active" Aβ plaques in two-photon imaging
Title:Oxalate-curcumin based probe for imaging reactive oxygen species at micro- and macro-levels in Alzheimer’s disease
Article link:DOI: 10.1073/pnas.1706248114
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