Hydrogels：GGA@Lipo@PTH(1-34)GLP pre-hydrogel
| 【Numbering】BKMB102012 | 【CAS】CAS | ||
| 【Item No.】BKMB102012-2 | 【specification】 | ||
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Name: GGA @ Lipo @ PTH (1-34) GLP pre-hydrogel
Composition: GGA polymers, Lipo @ PTH (1-34), and transglutaminase
Grain size: network structure
Application: Osteoarthritis
Storage conditions: -4℃
Other instructions: Half shelf life in sealed state [Main Advantage] teriparatide PTH (1-34) can be continuously released from GLP hydrogel, thus promote ATDC 5 cell proliferation by regulating the PI3K / AKT signaling pathway, and protect IL-1 β -induced ATDC 5 from further progression of OA. Furthermore, intra-articular injection of a hydrogel into an OA-induced mouse model promotes glycosaminoglycan synthesis and protects cartilage from degradation.
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Composition: GGA polymers, Lipo @ PTH (1-34), and transglutaminase
Grain size: network structure
Application: Osteoarthritis
Storage conditions: -4℃
Other instructions: Half shelf life in sealed state [Main Advantage] teriparatide PTH (1-34) can be continuously released from GLP hydrogel, thus promote ATDC 5 cell proliferation by regulating the PI3K / AKT signaling pathway, and protect IL-1 β -induced ATDC 5 from further progression of OA. Furthermore, intra-articular injection of a hydrogel into an OA-induced mouse model promotes glycosaminoglycan synthesis and protects cartilage from degradation.
Title:An injectable liposome-anchored teriparatide incorporated gallic acid-grafted gelatin hydrogel for osteoarthritis treatment.
Article link:https://mp.weixin.qq.com/s?src=11×tamp=1689126676&ver=4645&signature=*J8fqwiI6ZJymHQeYC9B2cZXcwnF9FLVH9B9R3KXqYUTCybZgCrdMna-upq5*I3Cxt0Cso-gKTKsB0fecGUQwvP37QVckWUAu6S8g*D1*xXetxm6NdKlKleV3m5pWwYk&new=1
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