Name: ADC HE-S2
Composition: PD-L1 THIOMAB D18
Application: Tumor therapy
Storage conditions: -4℃
Other instructions: Half year shelf life in sealed state [main advantage] not only triggers effective anti-tumor immune response by blocking PD-1 / PD-L1 interaction and activation of Toll-like receptor 7 / 8 (TLR 7 / 8) signaling pathway, but also regulates targeted PD-L1 through epigenetic regulation and / or IFN- γ -induced expression, thus conferring higher sensitivity to PD-1 / PD-L1 blockade.
Title:Immune Modulating Antibody–Drug Conjugate (IM-ADC) for Cancer Immunotherapy
Article link:https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00961
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