Nanozyme：PEG/Ce-Bi@DMSN
| 【Numbering】BKMA104018 | 【CAS】CAS | ||
| 【Item No.】BKMA104018-2 | 【specification】 | ||
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Name: PEG / Ce-Bi @ DMSN
Composition: CeO2, Bi2S3, DMSN, and PEG
Particle size: 100 nm
Application: Efficient tumor treatment
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [Main advantages] 1. Due to the presence of bismuth sulfide nanorods, The nanoenzyme showed good photothermal conversion efficiency (36.2%) with 1064 nm laser irradiation, Can realize the function of enzyme activity regulation of photothermal response; 2, the nanoenzyme showed dual enzyme-mimicking catalytic activity (peroxidase-like and catalase-like) under slightly acidic conditions, Can effectively modulate the tumor microenvironment, That is, it simultaneously increases oxidative stress and alleviates the resistance of tumor cells to reactive oxygen species caused by hypoxia; 3. The nanoenzyme can effectively deplete the overexpressed glutathione (GSH) in tumor cells through the redox reaction; 4, the two enzymatic activities of the nanoenzyme and the depletion capacity of GSH were well enhanced in a local photothermal environment.
Title:GSH‐Depleted Nanozymes with Hyperthermia‐Enhanced Dual Enzyme‐Mimic Activities for Tumor Nanocatalytic Therapy
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Composition: CeO2, Bi2S3, DMSN, and PEG
Particle size: 100 nm
Application: Efficient tumor treatment
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [Main advantages] 1. Due to the presence of bismuth sulfide nanorods, The nanoenzyme showed good photothermal conversion efficiency (36.2%) with 1064 nm laser irradiation, Can realize the function of enzyme activity regulation of photothermal response; 2, the nanoenzyme showed dual enzyme-mimicking catalytic activity (peroxidase-like and catalase-like) under slightly acidic conditions, Can effectively modulate the tumor microenvironment, That is, it simultaneously increases oxidative stress and alleviates the resistance of tumor cells to reactive oxygen species caused by hypoxia; 3. The nanoenzyme can effectively deplete the overexpressed glutathione (GSH) in tumor cells through the redox reaction; 4, the two enzymatic activities of the nanoenzyme and the depletion capacity of GSH were well enhanced in a local photothermal environment.
Title:GSH‐Depleted Nanozymes with Hyperthermia‐Enhanced Dual Enzyme‐Mimic Activities for Tumor Nanocatalytic Therapy
Article link:https://mp.weixin.qq.com/s?src=11×tamp=1688720143&ver=4635&signature=k1dPJvq*mT6dp4ppv*6nraPy3uMrwt4tgDFItJLCsVTJJhYoV7WF7uIXC1T4PUB3rXOAipZ0FRyQwFMaTsmpvyDXm63IXZgw-m492C0RvH7StPgrGDBc0WRabacDdSYj&new=1
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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