Hydrogels:Pe-hydrogel

Hydrogels:Pe-hydrogel

【Numbering】BKMB100022 【CAS】CAS
【Item No.】BKMB100022-2 【specification】
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Name: Pe-hydrogel
Composition: toll-like receptor 5
Particle size: 500nm
Application: Spray nano-micelle hydrogels and cell chips for the specific treatment of intestinal lesions
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantage] First, the peptide sequence is programmed with TLR 5 to inhibit its signal for anti-inflammatory treatment; second, during endoscopy, the injectable Pe hydrogel can be sprayed in the inflammatory area of the intestinal wall, and the temperature response of the second block copolymer produces sol-gel transition at body temperature, and specific adhesion to the inflamed area is helpful to accurately detect the intestinal damage and strengthen the therapeutic effect to restore the barrier function. In addition, the hydrogel of nano-micelle structure can enter the intestinal wall together with the peptide, which is beneficial to prolong the therapeutic effect.


Title:Sprayable nanomicelle hydrogels and inflammatory bowel disease patient

cell chips for development of intestinal lesion-specific therapy 

Article link:https://doi.org/10.1016/j.bioactmat.2022.03.031


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