Hydrogels:MZ@PNM@GCP水凝胶

Hydrogels:MZ@PNM@GCP水凝胶

【Numbering】BKMB100020 【CAS】CAS
【Item No.】BKMB100020-2 【specification】
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Name: MZ @ PNM @ GCP hydrogel
Composition: Metronidazole, penetration of nano-macrophages
Particle size: 200nm
Application: Nanopreparation based on penetrating macrophages for periodontitis
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] When hydrogel is embedded in the gingival sulcus, MZ @ PNM can target P.g. through the receptor on the macrophage membrane, and kill P.g. by cationic nanodrugs and the antimicrobial MZ. In addition, MZ @ PNM can also block the specific binding between P.g. and immune cells, neutralize the complement components, and timely prevent the destruction of P.g. immune response to periodontal hosts. The MZ @ PNM @ GCP hydrogel delivery system designed has shown strong efficacy in the treatment of periodontitis, restoring local immune function and killing pathogenic bacteria.


Title:Penetrating Macrophage-Based Nanoformulation for Periodontitis Treatment

Article link:https://doi.org/10.1021/acsnano.2c05923



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