Name: HPG-PPG-HPG hydrogel
Composition: HPG, PPG
Particle size: network structure, hole 20-100um
Application: Hydrated void hydrogels are used to encapsulate and continuously release small molecules
Storage conditions: -4℃
Other instructions: sealed state shelf life for half a year [main advantage] measure the absorbance at 492 nm to calculate the release rate, and using different models after the release of fluorescein sodium (FS), the results show that the release of FS in HVH is driven by diffusion, and not related to the hydrogel network structure change and polymer swelling behavior. In addition, the release rate of HVH to the loaded small molecules is mainly determined by the void size and the polymer hydration capacity, that is, the smaller gap and the higher hydration capacity will slow down the drug release rate.
Title:Hydration-Induced Void-Containing Hydrogels for Encapsulation and Sustained Release of Small Hydrophilic Molecules
Article link:https://doi.org/10.1002/adfm.202301025
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