Name: CH-OD-SSZ hydrogel
Composition: chitosan hydrochloride, dextran, sulfasalazine
Particle size: network structure, hole 20-100um
Application: injectable glucan-chitosan hydrogel to treat malignant ascites of liver cancer
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] Injectable hydrogel based on chitosan hydrochloride and oxidized dextran and loaded with iron death inducer sulfasalazine (SSZ) to improve antitumor effect. The in vitro release rate of SSZ in hydrogel (CH-OD-SSZ) is based on the solubility of hydrogel in CH-OD-SSZ and measured using high-performance liquid chromatography (HPLC), which shows that about three-quarters of SSZ is released within 72 hours.
Title:Ferroptosis-Enhanced Immunotherapy with an Injectable Dextran-Chitosan Hydrogel for the Treatment of Malignant Ascites in Hepatocellular Carcinoma
Article link:https://doi.org/10.1002/advs.202300517
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