Hydrogels:硫酸软骨素纳米凝胶

Hydrogels:硫酸软骨素纳米凝胶

【Numbering】BKMB100007 【CAS】CAS
【Item No.】BKMB100007-2 【specification】
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Name: Chondroitin sulfate nanogel
Composition: Aminomalonic acid 1-ethyl-3- (3-dimethylamino-propyl) carbon diimine hydrochloride CS
Particle size: 152 ± 7.27 nm, 131 ± 8.23 nm
Application: Cancer cell-specific delivery for CDDP
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [Main advantages] The release rate of CDDP in CS-nanogels is controlled by simple incorporation of PEG-PAEU hydrogel precursors, thus forming a microporous network of nanogel incorporation and being converted into nanogels at lower pH and temperatures. Cancer cell-specific targeting was significantly improved compared to normal cells. CS-nanogels containing both hydrogel precursors can form an in situ gel and are bioresorbable within 8 weeks after subcutaneous administration without causing significant inflammation.


Title:

Injectable hydrogels-incorporating cancer cell-specific cisplatin releasing
nanogels for targeted drug delivery

Article link:https://sci-hub.se/10.1039/c7tb00873b



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