Cu-TCPP(Cu)
| 【Numbering】BKC5190190 | 【CAS】 | ||
| 【Item No.】BKC5190190 | 【specification】 | ||
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【Major advantages】1. Slightly soluble in DMF, DMSO, etc. 2. Used as a biofluorescent probe for cell/in vivo detection. 3. Used as ligand to synthesize MOFs materials and as monatomic catalytic precursor. 4. In the presence of acid and hydrogen peroxide, the carboxyl group of TCPP ligand is oxidized and then reduced to peroxide radical under the action of peroxide and Cu2+, and singlet oxygen is generated by Russell recombination reaction, which is a therapy to overcome the limitation of photodynamic therapy. 5. Cu2+ in Cu-TCPP also consumes GSH. 6. PDT/PTT based on Cu-TCPP has combined anti-tumor efficacy and less systemic toxicity. 【Product performance and structure】A series of isomorphic porphyrin MOF was constructed by changing the type of metal at the center of metalloporphyrin ligand. A series of carbon-based monatomic catalyst materials with different metal centers (Cu, Fe, Co, Ni) were obtained after derivation, which can be used for PDT (excitation 660nm) and PTT (excitation 808nm) treatment.
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