Recombinant human epidermal growth factor
| 【Numbering】BK-NRPA11S | 【CAS】CAS | ||
| 【Item No.】BK-NRPA11S-1 | 【specification】 | ||
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Name: Recombinant human epidermal growth factor
Specifications: 10 μg, 100 μg, 1 mg, 10mg, special order
Product form: Lyophilized powder, the solution before lyophilization is 2.5 mM Na2HPO4, 2.5 mM NaH2PO4, 2% mannitol, pH 6.8 solution
Molecular weight: 6.2 kDa
Isoelectric point: 4.78
Source: Escherichia coli
Purity: ≥95% (SDS-PAGE and SEC-HPLC)
Endotoxin: ≤5 EU/mg
Activity: 1 mg≥1*106 U; EC50≤0.1 ng/ml (BALB/c 3T3 cell detection)
Storage conditions: -20℃ storage
Validity period: 3 years
Related introduction:
Mature human epidermal growth factor (hEGF) is a single-chain low-molecular-weight polypeptide composed of 53 amino acids, with a molecular weight of about 6.2 kDa, containing 6 cysteines in the molecule, and forming 3 pairs of disulfide bonds in the chain. , Alkali and heat are relatively stable, and can withstand the degradation of trypsin, chymotrypsin and pepsin and other enzymes. It is one of the most stable protein peptides known. hEGF exerts a variety of biological functions by binding to the specific EGF receptor (EGFR) on the cell surface, and can be used clinically to treat surgical trauma, skin ulcers, digestive tract ulcers, corneal injuries, tissue repair, etc.
hEGF can automatically bind to the EGFR on the cell membrane near the wound, thereby activating protein kinase, accelerating the synthesis of DNA, RNA and protein, promoting and regulating the growth and value of epidermal cells, allowing the wound to heal quickly and repairing skin tissue. Therefore, adding hEGF to cosmetics has the functions of removing scars, acne, and acne. hEGF also has a protective effect on normal skin, mainly in the aspects of delaying aging, increasing skin elasticity and luster.
The recombinant human epidermal growth factor (rh-EGF) is expressed by extracellular secretion, and the amino acid sequence and molecular structure remain consistent with the natural hEGF, and it has complete biological activity.
M: protein molecular weight standard
Lane 1: rh-EGF
rh-EGF stimulates the proliferation of BALB/c 3T3 cells (MTT method)
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Specifications: 10 μg, 100 μg, 1 mg, 10mg, special order
Product form: Lyophilized powder, the solution before lyophilization is 2.5 mM Na2HPO4, 2.5 mM NaH2PO4, 2% mannitol, pH 6.8 solution
Molecular weight: 6.2 kDa
Isoelectric point: 4.78
Source: Escherichia coli
Purity: ≥95% (SDS-PAGE and SEC-HPLC)
Endotoxin: ≤5 EU/mg
Activity: 1 mg≥1*106 U; EC50≤0.1 ng/ml (BALB/c 3T3 cell detection)
Storage conditions: -20℃ storage
Validity period: 3 years
Related introduction:
Mature human epidermal growth factor (hEGF) is a single-chain low-molecular-weight polypeptide composed of 53 amino acids, with a molecular weight of about 6.2 kDa, containing 6 cysteines in the molecule, and forming 3 pairs of disulfide bonds in the chain. , Alkali and heat are relatively stable, and can withstand the degradation of trypsin, chymotrypsin and pepsin and other enzymes. It is one of the most stable protein peptides known. hEGF exerts a variety of biological functions by binding to the specific EGF receptor (EGFR) on the cell surface, and can be used clinically to treat surgical trauma, skin ulcers, digestive tract ulcers, corneal injuries, tissue repair, etc.
hEGF can automatically bind to the EGFR on the cell membrane near the wound, thereby activating protein kinase, accelerating the synthesis of DNA, RNA and protein, promoting and regulating the growth and value of epidermal cells, allowing the wound to heal quickly and repairing skin tissue. Therefore, adding hEGF to cosmetics has the functions of removing scars, acne, and acne. hEGF also has a protective effect on normal skin, mainly in the aspects of delaying aging, increasing skin elasticity and luster.
The recombinant human epidermal growth factor (rh-EGF) is expressed by extracellular secretion, and the amino acid sequence and molecular structure remain consistent with the natural hEGF, and it has complete biological activity.
M: protein molecular weight standard
Lane 1: rh-EGF
rh-EGF stimulates the proliferation of BALB/c 3T3 cells (MTT method)
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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